قائمة األدوية األساسية للمملكة العربية السعودية

قائمة األدوية األساسية للمملكة العربية السعودية النسخة الثانية 2018 Essential Medicines of Saudi Arabia 2 nd List -2018

Class Generic Name Dosage Form Strength (Volume) 1 Anesthetics, Preoperative Medicines. 1.1 Injectable Medicines Ketamine 10 mg/ml (10ml); 50 mg/ml (10ml) Propofol 10 mg/ml 1.2 Local Anaesthetics Lidocaine 1% ; 2% Bupivacaine 0.25%; 0.5% Lidocaine+ Epinephrine 1%, 0.0005 %; 2%, 0.0005% 1.3 Preoperative medication and sedation for short-term procedures Atropine 1 mg Midazolam 5 mg/ml 1 mg/ml Morphine 10 mg/ml 2 Medicines for Pain and Palliative Care 2.1 Non- Opioids and NSAID Aspirin 81mg; 100mg; 320mg, 325mg; 650 mg Ibuprofen 200mg; 400mg; 600mg Oral Suspension 100 mg/ 5 ml Paracetamol 500 mg 120 mg/5ml Suppository 100mg; 200mg 10 mg/ml 2.2 Opioid analgesics Codeine Phosphate 30 mg Fentanyl Transdermal Patch 12 mcg/hr; 25 mcg/hr; 50 mcg/hr; 75 mcg/hr; 100 mcg/hr 2.3 Medicines for Other Common Symptoms in Palliative Care Amitriptyline 25mg; 50 mg Hyoscine butylbromide 20mg/ml Diazepam 5 mg/ml 2 mg/5ml 5mg; 10mg Rectal Solution 5mg; 10mg Lactulose 65 mg/100 ml Loperamide Capsule 2 mg 3 Antiallergics and Medicines Used in Anaphylaxis Dexamethasone 4mg/ ml 0.5 mg; 1.5 mg Epinephrine (adrenaline) 1mg/ml Hydrocortisone 100 mg Loratadine 1 mg/ml 10 mg Prednisolone 1mg/ml; 3mg/ml 5mg; 25mg 4 Antidotes And Other Substances Used In Poisonings Non-specific Charcoal, Activated Powder 50 G Specific Acetylcysteine 200 mg/ml Atropine 1 mg/ml Calcium Gluconate 10% Methylthioninium Chloride (methylene blue) 10 mg/ml (10 ml) Naloxone 0.02 mg/2ml;

0.4 mg/ml Penicillamine Capsule 250 mg Sodium Calcium edetate 200 mg/ml Sodium Thiosulfate 250 mg/ml Sodium Nitrite 30 mg/ml Deferoxamine Powder for 500 mg Dimercaprol 50 mg/ml Fomepizole 5 mg/ml ; 1g/ml 5 Anticonvulsants/Antiepileptics Carbamazepine Oral Suspension 100mg/5ml 200 mg Lamotrigine 25mg; 50mg; 100mg;200mg Chewable 5mg; 25mg; 100mg Lorazepam 1mg; 2mg Magnesium sulphate 10% ; 50% Phenobarbital 200 mg/ml 15 mg/5ml 15 mg to 100 mg Phenytoin 50 mg/ml 100 mg Capsule 100 mg Oral Suspension 30 mg/5ml Valproic Acid 200 mg (Valproate Sodium) Enteric-Coated 200 mg; 500 mg Oral Solution 200mg/5ml 6 Anti-Infective Medicines 6.1 Anthelminthics Albendazole 200 mg Ivermectin 3 mg Mebendazole 100 mg Niclosamide 500 mg Praziquantel 600 mg Diethylcarbamazine 50 mg 6.2 Antibacterial Amoxicillin Capsule 250 mg; 500 mg Oral Suspension 125 mg/5ml; 250 mg/5ml 500 mg Amoxicillin + Clavulanic Acid 156 mg/5ml; 228 mg/5ml; 312 mg/5ml; 475 mg/5ml 1 gm; 625 mg 1.2 gram; 600 mg Ampicillin 1gm; 500 mg Benzathine benzylpenicillin 1.2 million IU; 2.4 million IU Benzylpenicillin 1 million IU Phenoxymethylpenicillin Oral Suspension 250mg/5ml 250mg Cefalexin Oral Suspension 125 mg/ 5ml; 250mg/5ml Capsule 250 mg Cefazolin 1 gm Cefixime Capsule 200 mg; 400 mg Oral Suspension 100 mg/5ml

Cefuroxim 250 mg; 750 mg; 1.5 gm 125 mg; 250 mg; 500 mg Oral Suspension 125 mg/5ml; 250 mg/5ml Ceftriaxone 250 mg; 1 gm Cefotaxime 500 mg Ceftazidime 500 mg; 1 gm Cefepime 1 gm; 2 gm Cloxacillin 500 mg Pipracillin + Tazobactam 2250 mg; 4500 mg Meropenem 500 mg; 1gm Amikacin 250mg/ml Azithromycin Capsule 250 mg; 500 mg Oral Suspension 200 mg/5ml Chloramphenicol 1 gm 160mg/5ml Ciprofloxacin 250 mg 200 mg CLARITHROMYCIN 500mg Oral Suspension 125mg/5ml; 250mg/5ml CLINDAMYCIN 150mg/ml Doxycycline 100 mg 10 mg/ml Gentamicin 20 mg/2ml; 80 mg/2ml Metronidazole 250 mg; 500 mg Oral Suspension 200mg/5ml 5 mg/ml Nitrofurantoin 100 mg 25mg/5ml Sulfamethoxazole+ Trimethoprim 96 mg/ml 480 mg; 960 mg 48 mg/ml Vancomycin 500 mg; 1 gm Colistin 1 million I.U. Antituberculosis Ethambutol 400 mg Medicines Isoniazide 100 mg 50 mg/5ml Pyrazinamide 500 mg Rifampicin 150mg; 300mg 100 mg/5ml Streptomycin 1 gm 6.3 Antifungal Medicines Amphotericin B 50 mg Clotrimazole Vaginal cream 10% Vaginal 100 mg; 500 mg Fluconazole Capsule 50 mg 2 mg/ml Flucytosine 500 mg Griseofulvin 125mg; 500mg 125mg/5ml Itraconazole Capsule 100mg Nystatin Oral Suspension 100,000 IU/ml

Voriconazole 50mg; 200mg 200mg 6.4 Antiviral Medicines Aciclovir 200mg Oral Suspension 200 mg/5ml 250 mg 6.5 Antiretrovirals Abacavir 300 mg Lamivudine 150 mg Oral Solution 10 mg/ml Tenofovir Disoproxil Fumarate 245 mg Zidovudine Capsule 100 mg ORAL SOLUTION 50 mg/5 ml SOLUTION FOR 10 mg/ml INJECTION/INFUSION Efavirenz Capsule 200mg; 600 mg Nevirapine 200 mg Atazanavir Capsule 150 mg; 200 mg Darunavir 400 mg; 600 mg Lopinavir + Ritonavir 200 mg + 50 mg Ritonavir Oral Solution 80 mg/ml Dolutegravir 50 mg Fixed Dose Abacavir+ Lamivudine 300 mg+ 600 mg Combination Efavirenz + Emtricitabine + Tenofovir 600 mg + 200 mg + 300 mg Emtricitabine + Tenofovir 200 mg + 300 mg Lamivudine + Nevirapine + Zidovudine 150 mg + 200 mg + 300 mg Lamivudine + Zidovudine 150 mg + 300 mg 6.6 Other antivirals Ribavirin Capsule 200 mg Valganciclovir 450 mg 6.7 Anti-hepatitis medicines Entecavir 0.5 mg; 1 mg Sofosbuvir 400 mg Simeprevir Capsule 150 mg Daclatasvir 30 mg; 60 mg Dasabuvir 250 mg Ledipasvir + Sofosbuvir 90mg +400mg Ombitasvir +Paritaprevir + Ritonavir 12.5mg+75mg+50mg Fixed Dose Combination 6.8 Antiprotozoal Diloxanide 500 mg Chloroquine 10 mg/ml 150 mg Mefloquine 250 mg 7 Antineoplastic and Immunosuppressives Azathioprine 50 mg 50 mg Ciclosporin Capsule 25 mg Solution for Infusion 50 mg/ml Tretinoin Capsule 10 mg Asparaginase 10000 IU in vial Bendamustine 25mg; 100mg Bleomycin 15 mg Calcium folinate 3mg/ml; 10mg/ml Capecitabine 150mg; 500mg Carboplatin 10mg/ml Chlorambucil 2mg Cisplatin 50 mg Cyclophosphamide 50 mg

500mg Cytarabine 100 mg Dactinomycin 0.5 mg Dacarbazine 100 mg Dasatinib 20 mg; 50 mg; 70 mg Daunorubicin 20 mg Docetaxel 20 mg/ml; 40 mg/ml Doxorubicin 10 mg; 50 mg Etoposide 20 mg/ml Filgrastim 300mcg; 480mcg Fludarabine 50 mg 10 mg Fluorouracil 50 mg/ml Gemcitabine 200 mg; 1000 mg Hydroxycarbamide Capsule 500 mg Ifosfamide 500mg; 1 gm; 2 gm Imatinib 100 mg; 400 mg Irinotecan 20mg/ml Mercaptopurine 50 mg Mesna 100 mg/ml 400 mg; 600 mg Methotrexate 50 mg 2.5 mg Nilotinib 150 mg; 200 mg Oxaliplatin 5 mg/ml; 50 mg; 100 mg Paclitaxel 6 mg/ml Rituximab 10 mg/ml Trastuzumab 100 mg; 150 mg Vinblastine 1 mg/ml Vincristine 1 mg/ml Vinorelbine 10mg/ml Zoledronic acid 4mg/5ml; 0.8mg/ml 8 Hormones and Antihormones Anastrozole 1mg Leuprorelin 3.75 mg; 7.5 mg; 22.5 mg Methylprednisolone 500 mg; 40 mg/ml Tamoxifen 10 mg; 20 mg 9 Antiparkinsonism Medicines Levodopa + Carbidopa 25 mg +250 mg 10 Medicines Affecting The Blood 10.1 Antianaemia Medicines Ferrous salt syrup equivalent to 25 mg iron (as sulfate)/ ml equivalent to 60 mg iron Ferrous salt + folic acid equivalent to 60 mg iron + folic acid Folic Acid 1 mg; 5 mg Hydroxocobalamin 1 mg Epoetin alfa Solution for in Pre-filled Syringe 2000 IU/ml; 4000 IU/ml; 5000 IU/ml; 10000 IU/ml; 40000 IU/ml

10.2 Medicines Affecting Coagulation 10.3 Other Medicines For Haemoglobinopathies 11 Blood Products of Human Origin and Plasma Substitutes 11.1 Blood and blood components 1000 IU/ml; 4000 IU/ml; 40000 IU/ml Darbepoetin alfa Solution for in Pre-filled Syringe 15 mcg/0.375ml; 20 mcg/0.5ml; 30 mcg/0.3ml; 40 mcg/0.4ml; 50 mcg/0.5ml; 60 mcg/0.3ml; 80 mcg/0.4ml; 100 mcg/0.5ml; 150 mcg/0.3ml; 300 mcg/0.6ml; 500 mcg/ml Enoxaparin 20 mg; 40 mg; 60 mg; 80 mg Heparin sodium Solution for / 1000 U/ml; Infusion 5000 U/ml Solution for 25000 U/mL Protamine sulfate 10 mg/ml Warfarin 1 mg; 2 mg; 5 mg Vitamin k (Phytomenadione) 10 mg/ml; 1 mg Tranexamic acid 100 mg/ml Desmopressin Nasal spray 10 micrograms /dose Deferoxamine 500 mg Hydroxycarbamide (Hydroxyurea) Capsule 500 mg Fresh frozen plasma Platelet Red blood cells Whole blood 11.2 Human Normal Human Immunoglobulin Solution for 5%; 10% Immunoglobulins Anti-D immunoglobulin 250 IU 11.3 Blood Coagulation Coagulation factor VIII Powder for 500 IU Factors Solution for 500 IU; 1000 IU Coagulation factor IX Solution for 500 IU Powder for 1000 IU 12 Cardiovascular Medicines Spironolactone 25 mg Enalapril 5 mg; 10 mg Losartan Film Coated 25 mg; 50 mg; 100 mg Amiodarone 150 mg/3ml 200 mg Bisoprolol 2.5 mg; 5 mg Amlodipine 5 mg Verapamil 40 mg; 80 mg 2.5 mg/ml Clopidogrel 75 mg Digoxin Solution for 0.25 mg/ml Oral Liquid 0.05mg/ml 0.0625mg; 0.25 mg Epinephrine (adrenaline) 100 micogram/ml Dopamin 40 mg/ml Hydralazine 20 mg/ml 25 mg Lidocaine Solution for 2%

Methyldopa 250 mg Glyceryl Trinitrate (Nitroglycerin) Sublingual 500 mcg Isosorbide Dinitrate Sublingual 5 mg Sodium Nitroprusside 50 mg streptokinase 750000 IU Simvastatin 10 mg;20 mg;40 mg 13 Diuretics Furosemide 40 mg Solution for 20 mg/2 ml Oral Solution 1 mg/ml Hydrochlorothiazide 25 mg Mannitol 10%; 20% 14 Dermatological Medicines 14.1 Antifungal medicines Miconazole Cream 2% Terbinafine Cream 1% 14.2 Anti-infective medicines Mupirocin Ointment 2% Silver Sulfadiazine Cream 1% Betamethasone Cream; Ointment 0.1% Hydrocortisone Cream; Ointment 1% 14.3 Medicines affecting skin Benzoyl peroxide Gel 5% differentiation and Salicylic acid Ointment 10% proliferation 14.4 Scabicides and Benzyl benzoate Cutaneous solution 25% pediculicides 15 Diagnostic Agents 15.1 Ophthalmic medicines Fluorescein Eye drop 1% Tropicamide Eye drop 1% 15.2 Radiocontrast media Iohexol 180 mg - 300 mg 16 Disinfectants And Antiseptics Antiseptics Chlorhexidine Cutaneous liquid 4% w/v 17 Gastrointestinal medicines Pancreatin 170 mg 17.1 Antiulcer medicines Omeprazole Gastro-Resistant 10 mg; 20 mg; 40 mg Powder for 40 mg Ranitidine Film Coated 150 mg Solution for 25 mg/ml 15 mg/ml 17.2 Antiemetic medicines Metoclopramide 10 mg 5 mg/ml 10 mg/5ml Ondansetron Film Coated 4 mg; 8 mg Oral Solution 0.8 mg/ml Solution for 2 mg/ml 17.3 Anti-inflammatory Sulfasalazine 500 mg medicines 17.4 Laxatives Senna 20 mg 18 Medicines used in Diarrhoea Oral Rehydration Salts Powder Sachet 19 Hormones, other Endocrine Medicines 19.1 Adrenal hormones and synthetic substitutes Fludrocortisone 100 mcg 19.2 Insulins and other medicines used for diabetes Insulin Regular Solution for 100 IU/ml Intermediate -acting insulin Suspension for 100 IU/ml

Metformin Film Coated 500 mg; 1000 mg Gliclazide 30mg;60mg;80mg Glucagon Solution for 1 mg/ml 19.3 Ovulation inducers Clomifene 50 mg 19.4 Progestogens Medroxyprogesterone acetate 5 mg 19.5 Thyroid hormones and ant thyroid medicines Levothyroxine 150 mcg; 100 mcg; 50 mcg; 25 mcg Propylthiouracil 50 mg 20 Immunological Vaccines BCG vaccine Hepatitis A vaccine (Adult) Hepatitis A vaccine (Pediatric) Hepatitis B vaccine Measles vaccine Pneumococcal vaccine Meningococcal Meningitis vaccine Rotavirus vaccine Oral Suspension Oral Drops Varicella vaccine Haemophilus influenzae type b (Hib) Poliomyelitis Vaccine Oral Drops Diphtheria, Tetanus, Pertusis (DTaP) Measles, Mumps, Rubella(MMR) vaccine Tetanus Toxoid vaccine 21 Muscle Relaxants (peripherally-acting) and Cholinesterase Inhibitors Atracurium 1 mg/ml; 2 mg/ml; 5 mg/ml; 10 mg/ml Neostigmine 0.5mg/ml; 2.5mg/ml vecuronium 10 mg Suxamethonium chloride 100 mg/2ml 22 Ophthalmological Preparations 22.1 Anti-infective agents Aciclovir Eye Ointment 3% Erythromycin Eye Ointment 0.5% Gentamicin Eye Drops 0.3% Ofloxacin Eye Drops 0.3% Tetracycline Eye Ointment 1% 22.2 Anti-inflammatory Prednisolone acetate Eye Drops 1%; 0.12% agents 22.3 Miotics and Acetazolamide 250 mg antiglaucoma Latanoprost Eye Drops 50 mcg/ml medicines Timolol Eye Drops 0.25%; 0.5% Pilocarpine Eye Drops 2%; 4% 22.4 Mydriatics Atropine Eye Drops 0.5%; 1% 22.5 Local anaesthetics Tetracaine Eye Drops 1% 22.6 Anti-vascular Bevacizumab 25 mg/ml endothelial growth factor (VEGF) preparations 23 Oxytocics Oxytocics Misoprostol 200 mcg Vaginal 25 mcg Oxytocin 10 IU/ml 24 Peritoneal Dialysis Solution Intraperitoneal Dialysis Solution Parenteral solution

25 Medicines for Mental and Behavioral Disorders 25.1 Antipsychotic Chlorpromazine Oral Solution 25 mg/5ml 25 mg/ml Fluphenazine 25 mg/ml Haloperidol Oral Drops 2 mg/ml 0.5 mg; 2 mg; 5 mg Solution for 5 mg/ml Risperidone Film Coated 0.5 mg; 1 mg; 2 mg; 3 mg; 4 mg; 6 mg Clozapine 25 mg; 100 mg 25.2 Antidepressant Amitriptyline Capsule 25 mg; 50 mg Fluoxetine Capsule; 20 mg 25.3 Medicines used in Lithium carbonate 660 mg bipolar disorders 25.4 Medicines used for Clomipramine 10 mg; 25 mg obsessive compulsive disorders 25.5 Medicines for disorders Nicotine Replacement Therapy 2 mg; 4mg due to psychoactive Transdermal patch 17.5 mg; 35mg substance use 25.6 Other Methadone Oral Solution 2 mg/ml 26 Medicines Acting on the respiratory Tract Antiasthmatic Beclomethasone Inhalation Solution 250 mcg; 100 mcg; 50 mcg Inhalation Vapour 0.25 mg Budesonide Nebuliser Suspension 0.5 mg/ml; 0.25 mg/ml Inhalation Solution 200 mcg Inhalation Powder 100 mg; 200 mg Budesonide + Formoterol Dry powder inhaler 80mcg +4.5 mcg; 160mcg +4.5mcg Epinephrine (adrenaline) 1 mg/ml Ipratropium Bromide Pressurised Inhalation 0.2 mcg Salbutamol Pressurised 100 mcg Inhalation, Solution Inhalation Solution 0.5% Nebuliser Solution 2.5; 5 mg Solution for 0.5 mg/ml 27 Solutions Correcting Water, Electrolyte and Acid-Base Disturbances Dextrose Solution for 5% (isotonic) Solution for Infusion 10%; 50% (hypertonic) Dextrose + Sodium Chloride Solution for Infusion 5% +0.45%; 5% +0.9% Potassium chloride Solution for 7.5%; 15% Sodium Chloride Solution for 0.9% (isotonic ) Sodium bicarbonate Solution for 8.4% 28 Miscellaneous water for injection 2 ml; 5 ml; 10 ml 29 Vitamins and Minerals Ascorbic acid 1 gram Calcium 500 mg elemental Vitamin D3 (Cholecalciferol) Oral Drops 2800 IU/ml; 4500 IU/ml Capsule 5000 IU Retinol Capsule 50000 IU

Vitamin B6 (Pyridoxine) 40 mg Thiamine 50 mg 30 Ear, Nose and Throat Medicines Budesonide Nasal spray 50 mcg Ciprofloxacin Nasal Drops 3% Xylometazoline Nasal spray 0.05% 31 Specific Medicines for Neonatal Care Caffeine citrate 20 mg/ml Oral Solution 20 mg/ml Ibuprofen Solution for 5mg/ml Surfactant Intratracheal 27 mg/ml 32 Medicines For Diseases of Joint Allopurinol 100 mg; 300 mg Chloroquine 150 mg Hydroxychloroquine 200 mg SFDA criteria for including drugs in the Essential Medicines List: 1- WHO Essential Medicines List (2017) 2- Epidemic diseases in Saudi Arabia 3- First-line drugs 4- MOH Vaccination schedule This list was authorized by SFDA If you have any enquiries, suggestions or requests regarding the Essential Medicine List, please do not hesitate to contact the National Drug and Poison Information Center on the following channels: National Drug and Poison Information Center (NDPIC) Drug Sector Saudi Food and Drug Authority (SFDA) 3292 Northern Ring Road Riyadh, 13312-6288 Saudi Arabia Tel: 19999 E-mail: ndpic@sfda.gov.sa Web: https://dpic.sfda.gov.sa